Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Language outcome after perinatal stroke: does side matter?

Angela O Ballantyne1, Amy M Spilkin, Doris A Trauner

  • 1Department of Neuroscience, School of Medicine, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. aballant@crl.ucsd.edu

Child Neuropsychology : a Journal on Normal and Abnormal Development in Childhood and Adolescence
|September 14, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of COVID-19 Pandemic-Associated Social Changes on Boys with Moderate to Severe Autism.

Advances in neurodevelopmental disorders·2022
Same author

Editorial: Neurodevelopmental disabilities.

Current opinion in neurology·2019
Same author

Visual and verbal learning and memory in cystinosis.

Brain and cognition·2019
Same author

Heterozygous Variants in KMT2E Cause a Spectrum of Neurodevelopmental Disorders and Epilepsy.

American journal of human genetics·2019
Same author

Auditory neglect in children following perinatal stroke.

Behavioural brain research·2018
Same author

Chiari I Malformation in Nephropathic Cystinosis.

The Journal of pediatrics·2015
Same journal

Neurodevelopmental impacts of unique postnatal adversity subgroups in children with prenatal alcohol exposure.

Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence·2026
Same journal

Psychometric validation of the French adaptation of the Teenage Executive Functioning Inventory (TEXI) among adolescents.

Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence·2026
Same journal

Emotion regulation and social cognition in adolescents with tic disorders: associations with quality of life.

Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence·2026
Same journal

Longitudinal associations between preschool executive control and adolescent sleep: exploring the possible moderating role of negative affectivity.

Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence·2026
Same journal

Exploring cognitive diversity in a sample of children from Unsatisfied Basic Needs homes.

Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence·2026
Same journal

Normative reference values for executive function through the Early Years Toolbox (EYT) in preschoolers.

Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence·2026
See all related articles

Children with perinatal strokes show impaired language skills, regardless of brain hemisphere affected. Seizures significantly worsen language outcomes in these children.

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Pediatric Neurology

Background:

  • Perinatal strokes can lead to early focal brain lesions.
  • These lesions may impact neurodevelopmental outcomes, including language.
  • Structured language skills are crucial for academic and social success.

Purpose of the Study:

  • To investigate structured language abilities in school-age children with perinatal stroke-related brain lesions.
  • To compare language skills between children with left hemisphere (LH) and right hemisphere (RH) damage.
  • To identify factors influencing language outcomes in this population.

Main Methods:

  • Utilized the Clinical Evaluation of Language Fundamentals-Revised (CELF-R) to assess language skills.
  • Analyzed receptive, expressive, and total language scores.

Related Experiment Videos

  • Compared scores between 28 children with early focal brain lesions and 57 control participants.

    • Main Results:

    • Children with LH or RH damage performed significantly worse than controls on all language measures.
    • No significant differences were found between LH and RH groups.
    • Seizure occurrence was associated with significantly poorer language performance compared to non-seizure cases.

    Conclusions:

    • Early focal brain lesions from perinatal strokes adversely affect structured language abilities.
    • Lesion laterality, site, or severity did not significantly impact language outcomes.
    • Seizure activity is a critical factor influencing language prognosis in children with perinatal brain lesions.