Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Illicit cathinone ("Hagigat") poisoning.

Yedidia Bentur1, Anna Bloom-Krasik, Bianca Raikhlin-Eisenkraft

  • 1Israel Poison Information Center, Rambam Health Care Campus, The Bruce Rappaport Faculty of Medicine, Haifa, Israel. d_bentur@rambam.health.gov.il

Clinical Toxicology (Philadelphia, Pa.)
|September 14, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of recreational drug presentations to the emergency department in Europe, the Middle East and Northern Africa.

European journal of emergency medicine : official journal of the European Society for Emergency Medicine·2024
Same author

Severe outcomes following pediatric cannabis intoxication: a prospective cohort study of an international toxicology surveillance registry.

Clinical toxicology (Philadelphia, Pa.)·2023
Same author

The epidemiology of wild mushroom poisoning in Israel.

Mycologia·2023
Same author

Adherence of caregivers of children to advice provided by a National Poison Information Center.

Clinical toxicology (Philadelphia, Pa.)·2022
Same author

Adherence with prescription drugs in pregnant and breastfeeding women consulting with the Israel Poison Information Center Teratology Service.

Clinical toxicology (Philadelphia, Pa.)·2020
Same author

Arum palaestinum poisoning: revenge of the witch.

European journal of pediatrics·2020

Illicit cathinone exposure from Hagigat capsules caused serious cardiovascular and neurological issues, including heart attack and stroke, even in young individuals. This highlights the dangers of unregulated stimulant use.

Area of Science:

  • Toxicology
  • Pharmacology
  • Emergency Medicine

Background:

  • Khat leaves, containing cathinone and cathine, are traditional stimulants.
  • Hagigat, a product containing 200 mg cathinone, is marketed in Israel as a natural stimulant and aphrodisiac.
  • This study reports consequences of illicit cathinone exposure.

Purpose of the Study:

  • To investigate the clinical effects and outcomes of exposure to Hagigat (cathinone).
  • To document the toxicity associated with illicit cathinone consumption.

Main Methods:

  • A prospective observational study design was employed.
  • Data were collected from 34 patients reporting exposure to Hagigat via calls to a Poison Center over 10 months.
  • Patient records were reviewed, and telephone follow-up was conducted.

Related Experiment Videos

Main Results:

  • Thirty-four patients (aged 16-54) ingested or sniffed 0.5-6 capsules.
  • Common symptoms included headache, vomiting, hypertension, nausea, tachycardia, dyspnea, chest pain, and myalgia.
  • Severe complications like myocardial ischemia, pulmonary edema, and intracerebral hemorrhage occurred, notably in young patients.

Conclusions:

  • Illicit cathinone exposure is linked to significant cardiovascular and neurological toxicity.
  • Serious adverse events can occur even in young, otherwise healthy individuals.
  • Supportive treatment is crucial, with one case requiring neurosurgery.