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A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
Diterpenoid alkaloids from Delphinium gracile
M Reina1, R Mancha, A Gonzalez-Coloma
1Instituto de Productos Naturales y Agrobiología, CSIC, Avda. Astrofísico F. Sánchez 3, 38206 La Laguna, Tenerife, Spain. mreina@ipna.csic.es
Abstract:
Two highly oxygenated hetisine-type diterpenoid alkaloids, delphigraciline (1), 14-hydroxyhetisinone N-oxide (2), and the norditerpenoid alkaloid 8-methoxykarakoline (3), were isolated from a neutral extract of Delphinium gracile. Their structures were elucidated on the basis of spectroscopic data and by comparison with previously reported spectroscopic data of similar alkaloids. Their antiparasitic and insecticidal activities are also discussed.
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