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[Cutaneous manifestations of parvovirus B19 infection]

G Blaise1, A F Nikkels, G E Piérard

  • 1Service de Dermatopathologie, CHU du Sart Tilman, Liège, Belgique.

Revue Medicale De Liege
|September 15, 2007
PubMed

Insights

Human parvovirus B19, a common virus, primarily affects erythrocytes and endothelial cells. This review details its diverse cutaneous manifestations, including erythema infectiosum and the gloves and socks syndrome.

Area of Science:

  • Virology
  • Dermatology

Context:

  • Human parvovirus B19 (B19V) is a widespread virus affecting 60-70% of adults.
  • Transmission occurs via nasopharyngeal droplets.
  • B19V targets erythrocytes and endothelial cells via the P antigen receptor.

Purpose:

  • This review synthesizes current knowledge on B19V.
  • It focuses on the virus's cutaneous manifestations.
  • It also briefly covers systemic infections and less common dermatological associations.

Summary:

  • B19V causes systemic infections like aplastic anemia and hydrops fetalis.
  • Key dermatological findings include erythema infectiosum and papulo-purpuric gloves and socks syndrome.
  • Other reported, though less evidenced, skin conditions include vasculitis and lupus erythematosus-like syndrome.

Impact:

  • Provides a comprehensive overview of B19V's dermatological impact.
  • Aids clinicians in diagnosing and managing B19V-associated skin conditions.
  • Highlights areas for further research into B19V's pathogenesis and clinical spectrum.

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