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Updated: Jul 11, 2026

In Vitro Modeling of Fat Deposition in Metabolic Dysfunction-Associated Steatotic Liver Disease
Published on: July 19, 2024
Nonalcoholic fatty liver disease: pathogenesis, identification, progression, and management
Eric Yan1, Francisco Durazo, Myron Tong
1Center for Human Nutrition, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA. eyan@mednet.ucla.edu
Abstract:
Nonalcoholic fatty liver disease (NAFLD) encompasses a spectrum of liver diseases in the absence of significant alcohol consumption, and its incidence is paralleling the increasing numbers of overweight and obese individuals worldwide. This review discusses the pathogenesis of NAFLD, including the roles potentially played by specific adipokines, such as TNF-alpha, leptin, and adiponectin. Clinical features, diagnosis, and potential methods of management are also addressed to assist practitioners with the management of this growing population of patients.
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