[VEP in the determination of multiple lesions in the visual system in patients with multiple sclerosis]

18 patients with proven multiple sclerosis were examined by pattern reversal visual stimulation. Stimulations were carried out on full fields, foveal areas and horizontal half-fields of single eyes and on half-fields of both eyes. 77% of the patients demonstrated pathological alterations of the potentials in more than one kind of stimulation. In all patients pathological signs could be found, which pointed on the optic nerve. Only the results of three patients suggested a lesion within the central optic pathway. The demonstration of multiple lesions of the optic system in patients with multiple sclerosis is difficult and rarely possible.