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[The anti-inflammatory activity of structural analogs of the platelet-activating factor]

A G Melikiants, V I Kulikov, E E Koloskova

Farmakologiia I Toksikologiia

|July 1, 1991

Abstract:

The pro- and anti-inflammatory activity of new structural analogues of the platelet-activating factor (PAF) was studied. It was found that three PAF analogues inhibit PAF-induced rat paw edema in a dose-dependent manner. The anti-inflammatory activity of one of the PAF analogues upon PAF- or carrageenan-induced inflammation was comparable or in some extent exceeded that of dexamethasone.

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