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Published on: January 12, 2016
Cardiac history, prior depression and personality predict course of depressive symptoms after myocardial infarction
E J Martens1, O R F Smith, J Winter
1CoRPS - Center of Research on Psychology in Somatic Diseases, Tilburg University, The Netherlands. e.j.martens@uvt.nl
Insights
Depressive symptoms often persist after myocardial infarction (MI). Cardiac history, prior depression, and Type-D personality are key risk factors for persistent depression following MI.
Area of Science:
- Cardiology
- Psychiatry
- Psychology
Background:
- Limited understanding of the evolution and predictors of depressive symptoms in the first year post-myocardial infarction (MI).
- Previous research primarily focused on post-MI depression without detailing symptom trajectories.
Purpose of the Study:
- To examine the course of depressive symptoms during the first year after MI.
- To identify predictors of these depressive symptom trajectories.
Main Methods:
- Latent class analysis of Beck Depression Inventory scores from 287 MI patients at hospitalization, 2, and 12 months post-MI.
- Multinomial logit regression to identify predictors, including Type-D personality and cardiac history.
Main Results:
- Four distinct depressive symptom trajectories were identified: non-depressed (40%), mildly depressed (42%), moderately depressed (14%), and severely depressed (4%).
- Depressive symptoms remained stable throughout the first year post-MI.
- Cardiac history, history of depression, and Type-D personality were significant predictors of persistent depressive symptoms.
Conclusions:
- Depressive symptoms tend to persist in the first year following MI.
- Cardiac history, prior depression, and Type-D personality are independent risk factors for chronic depressive symptoms.
- Routine psychological screening post-MI is recommended to identify at-risk patients and mitigate negative prognostic effects.
Background:
Although many studies have focused on post-myocardial infarction (MI) depression, there is limited information about the evolution and determinants of depressive symptoms in the first year post-MI. Therefore we examined (1) the course of depressive symptoms during the first year post-MI and (2) the predictors of these symptom trajectories.
Method:
To assess depressive symptoms, 287 patients completed the Beck Depression Inventory during hospitalization for MI, and 2, and 12 months post-MI. Personality was assessed with the Type-D scale during hospitalization. We used latent class analysis to examine the evolution of depressive symptoms over a 1-year period and multinomial logit regression analyses to examine predictors of these symptom trajectories.
Results:
The course of depressive symptoms was stable during the first year post-MI. Four groups were identified and classified as non-depressed [40%, intercept (IC) 2.52], mildly depressed (42%, IC 6.91), moderately depressed (14%, IC 13.73) or severely depressed (4%, IC 24.54). In multivariate analysis, cardiac history (log OR(severe) 2.93, p=0.02; log OR(moderate) 1.81, p=0.02; log OR(mild) 1.46, p=0.01), history of depression (log OR(severe) 4.40, p<0.001; log OR(moderate) 1.97, p=0.03) and Type-D personality (log OR(severe) 4.22, p<0.001; log OR(moderate) = 4.17, p<0.001; log OR(mild) 1.66, p=0.02) were the most prominent risk factors for persistence of depressive symptoms during the first year post-MI.
Conclusions:
Symptoms of depression tend to persist during the first year post-MI. Cardiac history, prior depression and Type-D personality were identified as independent risk factors for persistence of depressive symptoms. The results of this study strongly argue for routine psychological screening during hospitalization for acute MI in order to identify patients who are at risk for chronicity of depressive symptoms and its deleterious effects on prognosis.
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