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[Heat stroke associated with massive hepatic necrosis].

S Sukenik1, S Livnat, M J Hausmann

  • 1Dept. of Medicine D, Soroka Medical Center, Beer Sheba.

Harefuah
|December 1, 1991
PubMed
Summary

Heat stroke can cause severe organ damage, including acute kidney injury and liver necrosis. Prompt supportive care and specific treatments led to a young soldier's full recovery.

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Area of Science:

  • Emergency Medicine
  • Nephrology
  • Hepatology

Background:

  • Heat stroke is a life-threatening condition characterized by hyperthermia and central nervous system dysfunction.
  • Military personnel are at increased risk due to strenuous physical activity in hot environments.

Observation:

  • A 21-year-old soldier experienced severe heat stroke.
  • Complications included acute renal failure, rhabdomyolysis, electrolyte imbalances (hypophosphatemia, hypocalcemia), sinus bradycardia, and massive liver necrosis.

Findings:

  • The patient underwent treatment with general supportive measures, forced alkaline diuresis, and intravenous administration of fresh frozen plasma and cryoprecipitate.
  • These interventions resulted in complete recovery from the severe multi-organ complications.

Implications:

  • This case highlights the critical importance of rapid diagnosis and aggressive management in heat stroke.
  • Effective treatment strategies can lead to favorable outcomes even in cases with extensive organ damage.
  • Understanding the complex pathophysiology of heat stroke is crucial for developing targeted therapies.

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