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Quantitative Measurement of γ-Secretase-mediated Amyloid Precursor Protein and Notch Cleavage in Cell-based Luciferase Reporter Assay Platforms
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Quantitative Measurement of γ-Secretase-mediated Amyloid Precursor Protein and Notch Cleavage in Cell-based Luciferase Reporter Assay Platforms

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Novel orally active, dibenzazepinone-based gamma-secretase inhibitors

Jens-Uwe Peters1, Guido Galley, Helmut Jacobsen

  • 1Pharma Division, Discovery Chemistry, F. Hoffmann-La Roche Ltd, CH-4070 Basel, Switzerland. jens-uwe.peters@roche.com

Bioorganic & Medicinal Chemistry Letters
|September 18, 2007
PubMed

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