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Updated: Jul 11, 2026

Visualizing the Effects of Sputum on Biofilm Development Using a Chambered Coverglass Model
Published on: December 14, 2016
Steady state model for evaluation of external and internal mass transfer effects in an immobilized biofilm
Sandeep Mudliar1, Saumita Banerjee, Atul Vaidya
1Environmental Biotechnology Division, National Environmental Engineering Research Institute (CSIR), Nehru Marg, Nagpur 440020, India. sn_mudliar@neeri.res.in
Abstract:
A steady model for the evaluation of external liquid film diffusion and internal pore diffusion effects in an immobilized biofilm system under continuous mode of operation was developed. The model takes into account, substrate diffusion through external liquid film and biofilm. Average rate of substrate consumption in the biofilm was considered. The overall efficiency of the biofilm was mathematically represented by considering the combined effects of substrate penetration and substrate utilization in the biofilm. The model was illustrated using a case study of pyridine biodegradation in a rotating biological contactor immobilized with pyridine degrading microbial film. The model is able to effectively predict both internal and external mass transfer effects in an immobilized biofilm system.
