Related Experiment Video
Updated: Jul 11, 2026

Using an Isolated Working Rat Heart Model to Test Donor Heart Preservation Strategies
Published on: October 4, 2024
When the heart remembers
1Department of Internal Medicine, University of Illinois, COM-UC, Urbana, IL 61801, USA. alizadeh@uiuc.edu
Abstract:
We present a 61-year-old patient who showed deep T wave inversion on her electrocardiogram (ECG) after cardioversion of her atrial flutter to sinus rhythm. A cardiac catheterization showed normal coronary arteries. The T wave inversion on her ECG is thought to be due to a cardiac memory phenomenon. Cardiac memory is a phenomenon that appears with T wave inversion on ECG after a change in the activation sequence of the heart. It may mimic cardiac ischemia and may mask any condition that appears with T wave abnormality on the ECG.
Related Concept Videos
Anatomy of the Heart
Anatomy of the Heart
The heart has three layers: the innermost endocardium, the muscular myocardium, and the outer epicardium, all working together for optimal cardiac function.
Chambers of the Heart
The heart is made up of four...
The Cardiac Cycle
The Process
Electrical signals—sent from the sinoatrial (SA) node in the right atrial wall to the atrioventricular (AV) node between the right atrium and right ventricle—cause both atria to simultaneously contract. When the signal reaches the AV node, it pauses for approximately a tenth of a second, allowing the atria to contract and empty blood into the...
Development of the Heart
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
Layers of the Heart Wall
The myocardium, the thickest layer, consists of cardiac muscle cells interconnected by intercalated discs and crisscrossing connective tissue fibers. These muscle fibers contract...
Physiology of the Heart: The Cardiac Cycle
Diastole: The Relaxation Phase
During diastole, all four heart chambers relax. The atrioventricular (AV) valves open, and the semilunar valves close. This phase sees the lowest chamber pressures, promoting ventricular filling. Venous blood enters the heart through the...
