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Related Experiment Video

Updated: Jul 11, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Published on: September 27, 2024

Nonablative tissue remodeling and photorejuvenation.

Danielle M DeHoratius¹, Jeffrey S Dover

¹Department of Dermatology, Section of Dermatologic and Cutaneous Oncology, Yale University School of Medicine, New Haven, CT 03536, USA.

Clinics in Dermatology

|September 18, 2007

Summary

Nonablative facial resurfacing offers a less invasive alternative to traditional methods for skin rejuvenation. Different lasers and light sources provide varied outcomes for texture, redness, and discoloration with minimal downtime.

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Published on: May 8, 2020

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Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

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Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ

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Published on: May 8, 2020

Area of Science:

Dermatology
Aesthetic Medicine
Cosmetic Procedures

Background:

Nonablative facial resurfacing provides a minimally invasive option for skin rejuvenation and tissue remodeling.
It serves as an alternative to traditional ablative laser resurfacing, offering reduced downtime.
Outcomes are dependent on the specific laser or light source utilized.

Purpose of the Study:

To summarize the efficacy of various nonablative lasers and light sources for facial skin rejuvenation.
To outline the differential effects of different energy-based devices on specific skin concerns.
To emphasize the importance of patient and device selection for optimal results.

Main Methods:

Review of current literature on nonablative facial resurfacing technologies.
Categorization of devices based on light spectrum (infrared, visible, intense pulsed light) and energy levels.
Analysis of reported outcomes for skin texture, redness, telangiectasias, and dyspigmentation.

Main Results:

Infrared lasers primarily enhance skin texture.
Visible light lasers improve texture and significantly reduce facial redness and telangiectasias.
Intense pulsed light devices address both red and brown pigmentary issues, alongside texture improvement.
Low-energy devices offer modest improvements in redness and texture.

Conclusions:

Nonablative resurfacing offers a versatile approach to skin rejuvenation with tailored device selection.
Patient selection based on desired outcomes is crucial for successful treatment.
Adverse effects are infrequent and can be mitigated through proper technique and patient management.