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Azathioprine for treatment of immune-mediated thrombocytopenia in two horses
K A Humber1, J Beech, T A Cudd
1Department of Clinical Studies, George D. Widener Hospital, New Balton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square 19348.
Journal of the American Veterinary Medical Association
|September 1, 1991
Abstract:
Azathioprine, a thiopurine antimetabolite used in the treatment of immune-mediated thrombocytopenia in human beings and dogs, was used in 2 cases of immune-mediated thrombocytopenia in horses that failed to respond to corticosteroid therapy alone. Platelet counts were increased to acceptable values in both horses. One horse returned to a successful racing career, and the other was euthanatized after developing renal disease and mild laminitis.