Related Experiment Video

Updated: Jul 11, 2026

Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome
06:39

Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome

Published on: October 3, 2018

Dyskeratosis congenita associated with hypocellular myelodysplastic syndrome: a case report

Hüseyin Engin1, Işinsu Kuzu, Yücel Ustündağ

  • 1Karaelmas University Faculty of Medicine, Department of Internal Medicine, Zonguldak, Turkey. bulengin@yahoo.com

The American Journal of the Medical Sciences
|September 18, 2007
PubMed

A 16-year-old female patient presented with complaints of malaise, dizziness, syncope, and nausea of 1-week duration. On dermatologic examination there were telangiectasias, atrophic areas, and poikiloderma with both hypopigmentation and hyperpigmentation on the neck and the proximal parts of the thighs. The bone marrow biopsy specimen showed hypocellularity and dysplastic megakaryocytic and erythroid elements, findings consistent with hypocellular myelodysplastic syndrome, which was further confirmed by cytogenetic studies. Thereafter, she was referred for allogeneic bone marrow transplantation.

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