Related Experiment Video
Updated: Jul 11, 2026
06:01
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Stroke attack rates and case fatality in the Krakow Stroke Registry
Agnieszka Słowik1, Wojciech Turaj, Grazyna Zwolińska
1Department of Neurology, Jagiellonian University College of Medicine, ul. Botaniczna 3, 31-503 Krakow, Poland. slowik@neuro.cm-uj.krakow.pl
Neurologia I Neurochirurgia Polska
|September 18, 2007
Summary
Stroke attack rates in Krakow, Poland, are comparable to European averages. However, recent data shows significantly lower short- and long-term stroke case fatality rates than previously observed.
Area of Science:
- Neurology
- Epidemiology
- Public Health
Background:
- Previous studies in Poland indicated moderate stroke incidence and high case fatality rates.
- The Krakow Stroke Registry provides updated epidemiological data.
Purpose of the Study:
- To determine current stroke attack rates in Krakow.
- To assess short- and long-term case fatality rates for stroke in hospitalized residents.
Main Methods:
- Prospective registration of all stroke cases (ICD-10) in adult residents of Krakow over one year (July 1999-June 2000).
- Vital status tracking at 30, 90, 180 days, and one year post-stroke.
Main Results:
- 1096 strokes recorded; standardized attack rate was 180.0 per 100,000 population.
- Ischaemic stroke (48.6%) and unspecified stroke (37.0%) were most common.
- One-year case fatality rate for all strokes was 39.7%; for ischaemic stroke 31.2%; for intracerebral haemorrhage 60.5%.
Conclusions:
- Stroke attack rates in urban Poland align with European averages.
- Current short- and long-term stroke case fatality rates are considerably lower than historical Polish data suggests.
Related Concept Videos
01:15Ischemic Stroke l: Introduction
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
01:17Hemorrhagic Stroke l: Introduction
A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
01:29Stroke: Introduction and Types
A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...
01:15Ischemic Stroke ll: Pathophysiology
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
01:29Hemorrhagic Stroke ll: Pathophysiology
A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
01:27Regulation of Stroke Volume
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...