Related Experiment Video
Updated: Jul 11, 2026

Venous Thrombosis Assay in a Mouse Model of Cancer
Published on: January 5, 2024
Renal vein thrombosis in transitional cell carcinoma
G Cilliers1, A Naidoo, C Ackermann
1Department of Radiology, University of Stellenbosch, Tygerberg Hospital, Cape Town, South Africa. glencilliers@absamail.co.za
A rare case of renal transitional cell carcinoma (TCC) with bland thrombus extending into the inferior vena cava is presented. This unique presentation, distinct from tumor thrombus, was diagnosed using CT scans aiding surgical planning.
Area of Science:
- Urology
- Oncology
- Radiology
Background:
- Renal transitional cell carcinoma (TCC) is a rare malignancy of the kidney.
- Tumor thrombus is common in renal cell carcinoma but rare in TCC.
- Bland thrombus in the renal vein associated with TCC is exceptionally rare.
Observation:
- A case of renal TCC with bland thrombus extending from the renal vein into the inferior vena cava was identified.
- Contrast-enhanced computed tomography (CT) was crucial for differentiating bland thrombus from tumor thrombus.
- The imaging findings directly informed the surgical approach and management strategy.
Findings:
- This report describes the first documented instance of bland renal vein thrombosis co-occurring with renal TCC.
- CT imaging proved effective in distinguishing bland thrombus from tumor thrombus in this specific context.
- Accurate thrombus characterization facilitated appropriate surgical intervention.
Implications:
- Highlights the importance of advanced imaging in diagnosing rare vascular complications of renal TCC.
- Adds to the understanding of the diverse clinical presentations of renal transitional cell carcinoma.
- Emphasizes the need for careful radiological assessment to guide surgical management in complex renal masses.
Related Concept Videos
Venous Thrombosis I: Introduction
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Venous Thrombosis III: Interprofessional Care
Veins of the Abdomen and Pelvis
The inferior vena cava is fed by numerous smaller veins. The lumbar veins, for instance, drain the posterior abdominal wall, emptying both directly into the inferior vena cava and into the...
Venous Thrombosis IV: Nursing Management
Veins of Thorax
The azygos vein, positioned just right of the midline and anterior to the vertebral column, begins at the junction of the right ascending lumbar and subcostal veins, terminating in the superior vena cava. This vein drains blood from the right side of the thoracic wall, thoracic viscera, and posterior abdominal wall.
The...

