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Updated: Jul 11, 2026

Measuring the Motor Aspect of Cancer-Related Fatigue using a Handheld Dynamometer
Published on: February 20, 2020
[Relation between fatigue and autonomic disturbances in multiple sclerosis]
Andréa Temponi Lebre1, Maria Fernanda Mendes, Charles P Tilbery
1Faculdade de Ciências Médicas, Disciplina de Neurologia, Santa Casa de São Paulo, São Paulo, SP, Brazil. atlebre@ig.com.br
Abstract:
Fatigue is a common symptom in multiple sclerosis (MS). The objective of this study was to relate fatigue and autonomic disturbances in MS. Fifty patients with MS relapsing remitting clinical form participated in this study. Thirty three (66%) were women and 17 (34%) men. Score less or equal to 3.5 in the EDSS. Five non invasive cardiovascular tests were applied in all patients for the sympathetic and parasympathetic evaluation. The results obtained in the hand grip test were increased in the blood pressure of 14.62 +/- 9.13 mmHg for the group with fatigue and of 21.68 +/- 7.18 mmHg for the non fatigue group. This difference was statistically significant (p<0.05). Conclusion is that there is a loss in the capacity to increase blood pressure in patients with fatigue suggesting a sympathetic dysfunction.
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