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Modeling Posthemorrhagic Hydrocephalus of Prematurity in Rats
Published on: March 28, 2025
[Clinical and evolutive aspects of hydrocephalus in neurocysticercosis]
Svetlana Agapejev1, Ana Flávia P Pouza, Rodrigo Bazan
1Departamento de Neurologia e Psiquiatria, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista Júlio de Mesquita Filho, 18618-000 Botucatu, SP, Brazil. agapejev@fmb.unesp.br
Abstract:
With the purpose to verify clinical aspects of hydrocephalus (HC) in patients with neurocysticercosis (NCC), a retrospective study of 47 patients was performed. The majority of patients (70.2%) were men aging 21-50 years. Intracranial hypertension (ICH) occurred in all patients, headache (HA) in 42 (89.4%), meningoencephalitis (ME) in 38 (80.8%) and psychiatric disorders (PD) in 34 (72.3%). The cerebrospinal fluid syndrome of NCC was detected in 31 patients (65.9%). In addition to HC, computed tomography (CT) scans showed cystic lesions in 28 (59.6%) patients, diffuse brain edema also in 28 (59.6%), and calcifications in 26 (55.3%). Shunts were inserted in 41 (87.2%) patients and 22 (53.7%) of them were submitted to 1-7 surgical revision/patient (mean=3) that were higher (mean=4) in those who died than in survivors (mean=2). Evolution was satisfactory in 24 (51.1%) patients and fatal in 15 (31.9%). It is possible to conclude that, in patients with NCC, HC occurs predominantly in men in productive life with ICH, HA, ME and PD as common manifestations, and the need for shunt revision makes patient's prognosis worse.
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