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Ethnic disparity in outcomes for pediatric peritoneal dialysis patients in the ESRD Clinical Performance Measures
Meredith A Atkinson1, Alicia M Neu, Barbara A Fivush
1Pediatric Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. matkins3@jhmi.edu
Insights
Hispanic pediatric patients on peritoneal dialysis show similar or better intermediate outcomes compared to non-Hispanic patients. This study analyzed outcomes for pediatric End-Stage Renal Disease patients, focusing on Hispanic ethnicity.
Area of Science:
- Nephrology
- Pediatric Nephrology
- Public Health
Background:
- End-Stage Renal Disease (ESRD) affects pediatric populations, with varying outcomes across ethnic groups.
- Peritoneal dialysis (PD) is a key treatment modality for pediatric ESRD.
- Understanding ethnic disparities in PD intermediate outcomes is crucial for equitable care.
Purpose of the Study:
- To determine associations between intermediate outcomes and Hispanic ethnicity in pediatric PD patients.
- To compare PD intermediate outcomes between Hispanic and non-Hispanic pediatric patients.
- To identify potential disparities in PD care for Hispanic children with ESRD.
Main Methods:
- Retrospective cohort study using data from the ESRD Clinical Performance Measures (CPM) Project (October 2004 - March 2005).
- Inclusion of all pediatric PD patients within the study period.
- Analysis of intermediate outcomes including dialysis clearance, hemoglobin, and serum albumin levels, stratified by ethnicity.
Main Results:
- Hispanic patients constituted 30% of the cohort; they were more likely to be female and older with lower mean height SDS.
- No significant differences in clearance parameters were observed among ethnic groups.
- Hispanic patients showed significantly higher rates of achieving target hemoglobin (> or = 11 g/dl) and serum albumin (> or = 4.0/3.7 g/dl BCG/BCP) compared to non-Hispanic whites and blacks.
Conclusions:
- Pediatric Hispanic PD patients achieve equivalent or superior intermediate outcomes in dialytic care compared to non-Hispanic counterparts.
- Hispanic ethnicity is associated with better achievement of key nutritional and hematological markers in pediatric PD.
- Further research is warranted to explore associations between Hispanic ethnicity and long-term outcomes like hospitalization, transplantation, and mortality.
Abstract:
Ethnicity information was collected for all pediatric peritoneal dialysis patients from the End-Stage Renal Disease (ESRD) Clinical Performance Measures (CPM) Project for the period October 2004 through March 2005. Associations between intermediate outcomes and Hispanic ethnicity were determined. Thirty percent (207/696) of patients in the final cohort were Hispanic, 24% (165/696) non-Hispanic black, and 46% (324/696) non-Hispanic white. Hispanics were more likely to be female, older, and have a lower mean height standard deviation score (SDS). There were no significant differences among ethnic/racial groups regarding clearance parameters. More Hispanics had a mean hemoglobin > or = 11 g/dl compared with non-Hispanic blacks and non-Hispanic whites (77% vs. 55% and 70%, P < 0.0001). More Hispanics compared with non-Hispanic blacks and non-Hispanic whites had a mean serum albumin > or = 4.0/3.7 g/dl [bromcresol green/bromcresol purple laboratory method (BCG/BCP)] (50% vs. 24% and 27%, respectively, P < 0.0001). In multivariate analyses, Hispanics remained significantly more likely to achieve a mean serum albumin > or = 4.0/3.7 g/dl (BCG/BCP) compared with non-Hispanic whites (referent) and were as likely to achieve clearance and hemoglobin targets. Pediatric Hispanic peritoneal dialysis patients experience equivalent or better intermediate outcomes of dialytic care compared with non-Hispanics. Further study is needed to understand associations of Hispanic ethnicity with outcomes such as hospitalization, transplantation, and mortality.
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