Ethnic disparity in outcomes for pediatric peritoneal dialysis patients in the ESRD Clinical Performance Measures

Meredith A Atkinson1, Alicia M Neu, Barbara A Fivush

  • 1Pediatric Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. matkins3@jhmi.edu

Insights

Hispanic pediatric patients on peritoneal dialysis show similar or better intermediate outcomes compared to non-Hispanic patients. This study analyzed outcomes for pediatric End-Stage Renal Disease patients, focusing on Hispanic ethnicity.

Area of Science:

  • Nephrology
  • Pediatric Nephrology
  • Public Health

Background:

  • End-Stage Renal Disease (ESRD) affects pediatric populations, with varying outcomes across ethnic groups.
  • Peritoneal dialysis (PD) is a key treatment modality for pediatric ESRD.
  • Understanding ethnic disparities in PD intermediate outcomes is crucial for equitable care.

Purpose of the Study:

  • To determine associations between intermediate outcomes and Hispanic ethnicity in pediatric PD patients.
  • To compare PD intermediate outcomes between Hispanic and non-Hispanic pediatric patients.
  • To identify potential disparities in PD care for Hispanic children with ESRD.

Main Methods:

  • Retrospective cohort study using data from the ESRD Clinical Performance Measures (CPM) Project (October 2004 - March 2005).
  • Inclusion of all pediatric PD patients within the study period.
  • Analysis of intermediate outcomes including dialysis clearance, hemoglobin, and serum albumin levels, stratified by ethnicity.

Main Results:

  • Hispanic patients constituted 30% of the cohort; they were more likely to be female and older with lower mean height SDS.
  • No significant differences in clearance parameters were observed among ethnic groups.
  • Hispanic patients showed significantly higher rates of achieving target hemoglobin (> or = 11 g/dl) and serum albumin (> or = 4.0/3.7 g/dl BCG/BCP) compared to non-Hispanic whites and blacks.

Conclusions:

  • Pediatric Hispanic PD patients achieve equivalent or superior intermediate outcomes in dialytic care compared to non-Hispanic counterparts.
  • Hispanic ethnicity is associated with better achievement of key nutritional and hematological markers in pediatric PD.
  • Further research is warranted to explore associations between Hispanic ethnicity and long-term outcomes like hospitalization, transplantation, and mortality.

Related Concept Videos

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications

Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis01:30

Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis

Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
Peritoneal Dialysis III: Nursing Management01:25

Peritoneal Dialysis III: Nursing Management

Peritoneal dialysis, or PD, utilizes the peritoneal membrane as a filter to eliminate excess fluid and waste products. Effective nursing management is essential for ensuring patient safety, preventing complications, and promoting optimal function of the peritoneal dialysis process.Assessment and MonitoringNurses must thoroughly assess the patient before, during, and after each dialysis session. Regular monitoring includes vital signs, daily weight, fluid intake and output, and laboratory values...
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration01:28

Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration

Glomerular filtration rate (GFR) can be estimated from serum creatinine using the modification of diet in renal disease (MDRD) formula or the chronic kidney disease–epidemiology collaboration (CKD–EPI) equation. Both methods are widely used in clinical practice to assess kidney function and guide treatment decisions.The MDRD equation does not require weight or height measurements and is normalized to the body surface area of 1.73 m², considered the average adult surface area. This equation is...
Peritoneal Dialysis I: Introduction and Procedure01:30

Peritoneal Dialysis I: Introduction and Procedure

Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...