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Updated: Jul 11, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
[Perinatal depression--recent topics]
1Centre for Health, Mie University.
Depression is the most common complication in perinatal period, affecting approximately 10% of women. Studies were also examined for data related to the predictors/risk factors, effects on the fetus and newborn, and treatment of depression during these periods. Psychopharmacological treatment in pregnant or breastfeeding women with depression will result primarily from a careful evaluation of their psychopathological condition. Maternal depression is associated with adverse effects on fetal and infant development. Prevention and psychological intervention is also useful for detecting mother with postnatal depression, using the EPDS. Controlled psychological trials for postnatal depression have shown the benefit of involving health professionals. Multidisciplinary specialist teams in mother and baby units have been an important role in perinatal psychiatric care.
Depression is the most common complication in perinatal period, affecting approximately 10% of women. Studies were also examined for data related to the predictors/risk factors, effects on the fetus and newborn, and treatment of depression during these periods. Psychopharmacological treatment in pregnant or breastfeeding women with depression will result primarily from a careful evaluation of their psychopathological condition. Maternal depression is associated with adverse effects on fetal and infant development. Prevention and psychological intervention is also useful for detecting mother with postnatal depression, using the EPDS. Controlled psychological trials for postnatal depression have shown the benefit of involving health professionals. Multidisciplinary specialist teams in mother and baby units have been an important role in perinatal psychiatric care.
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