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Cholesterol Efflux Assay
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Cholesterol Efflux Assay

Published on: March 6, 2012

Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis

Chun-Lin Chen1, I-Hua Liu, Steven J Fliesler

  • 1Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, 1402 S. Grand Blvd., St Louis, MO 63104, USA.

Journal of Cell Science
|September 20, 2007
PubMed
Summary

High cholesterol impairs TGF-beta signaling, a key pathway in cardiovascular health. Lowering cholesterol levels restores this crucial cellular response, potentially preventing atherosclerosis.

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