[Devic's neuro-optic myelitis and pregnancy]

Area of Science:

• Neuroscience
• Ophthalmology
• Neurology

Background:

• Devic's neuromyelitis optica is an autoimmune disorder affecting the optic nerves and spinal cord.
• It is characterized by optic neuritis and acute transverse myelitis.
• Pregnancy is a rare but potential trigger for this condition.

Observation:

• A 20-year-old pregnant woman presented with sudden, severe bilateral vision loss.
• She subsequently developed spastic paraplegia and sphincter dysfunction.
• Diagnosis was confirmed via cerebrospinal fluid analysis and MRI.

Findings:

• Prompt treatment with high-dose corticosteroids (prednisolone) resulted in significant improvement.
• Neurological and visual deficits stabilized within one year.
• The case underscores the importance of timely diagnosis and management.

Implications:

• This case contributes to understanding Devic's neuromyelitis optica in pregnancy.
• It supports the classification of Devic's disease as distinct from multiple sclerosis.
• Effective management strategies can lead to favorable outcomes even in complex cases.