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Updated: Jul 11, 2026

Preparation of Functional Silica Using a Bioinspired Method
Published on: August 1, 2018
Silenes in organic synthesis: a concise synthesis of (+/-) -epi-picropodophyllin
Robert D C Pullin1, Jonathan D Sellars, Patrick G Steel
1Department of Chemistry, University of Durham, Science Laboratories, Durham, UK.
Abstract:
A concise, seven step synthesis of the aryl tetralin lignan lactone epi-picropodophyllin from piperonal is described. The key steps are a silene diene Diels-Alder reaction and the Hosomi-Sakurai reaction of the resultant silacyclohexene.
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