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Published on: August 19, 2020
Nephrotic syndrome resulting from focal segmental glomerulosclerosis in a peripheral blood stem cell transplant
Manuel Heras1, Ana Saiz, Rosa Sánchez
1Department of Nephrology, Segovia General Hospital, Segovia, Spain.
Abstract:
We describe the case of a male patient who was diagnosed with acute monoblastic leukemia and received a peripheral stem cell transplantation (PSCT) with peripheral blood hematopoietic progenitors. Because he was in clinical remission with no evidence of chronic graft-versus-host disease (GVHD), immunosuppression was withdrawn, and he developed nephrotic syndrome (NS) months later. A kidney biopsy showed focal segmental glomerulosclerosis (FSGS) as part of the GVHD. Soon after the reintroduction of previous immunosuppressive therapy, we observed a complete remission of the NS.
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