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Updated: Jul 11, 2026
Analysis of Lymph Node Volume by Ultra-High-Frequency Ultrasound Imaging in the Braf/Pten Genetically Engineered Mouse Model of Melanoma
Published on: September 8, 2021
The evolution of the management of regional lymph nodes in melanoma
Christine S Landry1, Kelly M McMasters, Charles R Scoggins
1Division of Surgical Oncology, Department of Surgery, University of Louisville School of Medicine, Louisville, KY 40202, USA.
Abstract:
The last two decades have seen sweeping changes in the surgical approach to melanoma. Traditionally, patients without evidence of nodal metastases were considered for elective lymph node dissection. This approach placed many patients at risk of morbidity while many derived no benefit. As investigators gained a deeper understanding of melanoma and lymphatic biology, newer methods of managing regional lymph nodes were sought. The advent of sentinel node biopsy has radically changed the approach to melanoma.
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