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Related Experiment Video

Updated: Jul 11, 2026

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
07:51

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy

Published on: June 1, 2019

Sentinel lymph node biopsy for breast cancer.

K Sato1, R Shigenaga, S Ueda

  • 1Department of Surgery, Self-Defense Forces Central Hospital, Setagaya, Tokyo, Japan.

Journal of Surgical Oncology
|September 20, 2007
PubMed
Summary

This review covers the evolution of radiotracer guided surgery for sentinel lymph nodes (SNs) in breast cancer. It highlights historical contributions, current research volume, and future technical challenges in SN procedures.

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Area of Science:

  • Oncology
  • Surgical Innovation
  • Medical Imaging

Background:

  • Sentinel lymph node (SN) biopsy is crucial for breast cancer staging.
  • Radiotracer technology has significantly advanced SN identification.
  • Understanding the historical context informs current and future SN procedures.

Purpose of the Study:

  • To review the technological and conceptual developments in radiotracer guided sentinel node surgery for breast cancer.
  • To acknowledge key historical contributions to SN methods.
  • To outline the current landscape of SN research and future challenges.

Main Methods:

  • Literature review of historical contributions to SN methods.
  • Analysis of the volume and types of published SN research.

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Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
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Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

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Last Updated: Jul 11, 2026

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
07:51

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Published on: June 1, 2019

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
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Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

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  • Discussion of ongoing international trials and technical hurdles in SN surgery.

    • Main Results:

    • The evolution from early concepts to modern radiotracer guided SN surgery is detailed.
    • A significant body of published material on SN procedures exists.
    • Major international trials are underway, with technical challenges remaining.

    Conclusions:

    • Radiotracer guided sentinel node surgery has evolved significantly due to technological advancements.
    • Continued research and international collaboration are essential for addressing remaining technical challenges in SN procedures.
    • The field is poised for further innovation in breast cancer management.