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[Study on chemical constituents in rhigome of Ervatamia hainanensis]
Shuang Liang1, Hai-sheng Chen, Yong-sheng Jin
1College of Pharmacy, Second Military Medical University, Shanghai 200433, China.
Objective:
To investigate the chemical constituents of the rhizome of Ervatamia hainanensis.
Method:
The solvent extraction and silica column chromatography were used to separate the chemical constituents, and their structures were identified by physico chemical properties and spectra analysis.
Result:
Twelve compounds were isolated and their structures were identified as voacangine (1), ibogaine (2), ibogamine (3), coronaridine (4), 19-heyneanine (5), 19-epi-heyneanine (6), 3-hydroxyl coronaridine (7), coronaridine hydroxyindolenine (8), 3-(2-oxopropyl) coronaridine (9), vobasine (10), alpha-amyrin (11), alpha-amyrin acetate (12).
Conclusion:
Compounds 1, 2, 6, 11 and 12 were first found from this plant.
