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Isolated lichen planus of the lip
M Petruzzi1, M De Benedittis, L Pastore
1Department of Dentistry and Surgery, University of Bari, Bari, Italy. m.petruzzi@doc.uniba.it
International Journal of Immunopathology and Pharmacology
|September 21, 2007
Summary
Isolated oral lichen planus (OLP) of the lip, though uncommon, presents a diagnostic challenge. This case series found the atrophic-erosive form most frequent and showed good response to topical corticosteroids and tocopherol oil.
Area of Science:
- Oral Medicine
- Dermatology
- Pathology
Background:
- Oral lichen planus (OLP) is a common inflammatory condition affecting the oral mucosa.
- While typically seen on the buccal mucosa, OLP can rarely present isolated to the lips, posing diagnostic difficulties.
Purpose of the Study:
- To describe a case series of patients with isolated lip OLP.
- To identify the clinical variants, associated conditions, and treatment outcomes for isolated lip OLP.
Main Methods:
- A case series of ten patients with isolated lip OLP was reviewed.
- Clinical data including medical history, oral examination, signs, and symptoms were recorded.
- Treatment response to topical clobetasol propionate and tocopherol oil was assessed.
Main Results:
- The atrophic-erosive form was the most common clinical variant.
- Five patients had co-existing Hepatitis C Virus (HCV) hepatitis.
- Eight patients achieved complete remission with topical treatment; the remainder showed partial improvement.
Conclusions:
- Isolated OLP of the lip is an unusual presentation requiring careful differential diagnosis.
- Topical corticosteroids and tocopherol oil are effective treatments for lip OLP.
- Early diagnosis and management are crucial and may potentially reduce squamous cell carcinoma risk.
