Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Metabolic bone diseases].

F Jakob1

  • 1Orthopädisches Zentrum für Muskuloskelettale Forschung, Lehrstuhl Orthopädie, Orthopädische Klinik König-Ludwig-Haus, Universität Würzburg, Brettreichstrasse 11, 97074, Würzburg, Germany. f-jakob.klh@mail.uni-wuerzburg.de

Der Internist
|September 21, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Immune and stem cell compartments of acetabular and femoral bone marrow in hip osteoarthritis patients.

Osteoarthritis and cartilage·2022
Same author

Effects of different exercise intensity on bone mineral density in adults: a comparative systematic review and meta-analysis.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2022
Same author

Molecular weight dependent structure of the exopolysaccharide levan.

International journal of biological macromolecules·2020
Same author

Hypophosphatasia in adolescents and adults: overview of diagnosis and treatment.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2020
Same author

The inflamed biceps tendon as a pain generator in the shoulder: A histological and biomolecular analysis.

Journal of orthopaedic surgery (Hong Kong)·2019
Same author

JAM-A as a prognostic factor and new therapeutic target in multiple myeloma.

Leukemia·2017
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
Same journal

Der Internist·2024
See all related articles

Osteomalacia and osteoporosis are bone diseases often caused by vitamin D deficiency and impaired calcium metabolism. Treatment involves optimizing nutrient intake, hormone replacement, and fall prevention strategies to reduce fracture risk.

Area of Science:

  • Endocrinology
  • Metabolic Bone Disease
  • Geriatric Medicine

Context:

  • Osteomalacia results from impaired vitamin D receptor (VDR) signaling, calcium deficiency, and altered bone mineralization.
  • Causes include low sunlight, malabsorption, reduced vitamin D activation in chronic kidney disease, and rare VDR/phosphate metabolism defects.
  • Osteoporosis is defined by bone fragility and fractures from minor trauma.

Purpose:

  • To summarize the causes, symptoms, and management strategies for osteomalacia and osteoporosis.
  • To highlight diagnostic criteria and therapeutic interventions for reducing fracture risk.

Summary:

  • Osteomalacia symptoms include bone pain, muscle cramps, and falls; management involves optimizing calcium and vitamin D3 intake, and replacing active vitamin D and phosphate if deficient.

Related Experiment Videos

  • Osteoporosis diagnosis relies on absolute fracture risk assessment (bone density, age, sex, risk factors).
  • Effective interventions for osteoporosis include exercise, fall prevention programs, and pharmacotherapy, significantly reducing fracture risk, especially in the elderly. Secondary osteoporosis requires treating underlying conditions alongside bone-modifying drugs.

    • Impact:

    • Provides a comprehensive overview of two significant metabolic bone diseases.
    • Informs clinical practice regarding diagnosis and management of osteomalacia and osteoporosis.
    • Emphasizes the importance of early detection and multidisciplinary approaches for fracture risk reduction.