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Updated: Jul 11, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Primary resection and anastomosis for complicated meconium ileus: a safe procedure?
Jhalini Jawaheer1, Basem Khalil, Tyasha Plummer
1Department of Neonatal Surgery, St Mary's Hospital for Women and Children, Manchester, UK.
Insights
Resection and primary anastomosis is a safe surgical option for complicated meconium ileus (MI). This method offers a shorter hospital stay and avoids a second surgery for stoma closure.
Area of Science:
- Pediatric Surgery
- Gastrointestinal Surgery
Background:
- Meconium ileus (MI) is a common surgical emergency in neonates.
- Various surgical interventions exist for MI, each with potential complications.
Purpose of the Study:
- To evaluate the safety and efficacy of resection and primary anastomosis (RA) for complicated meconium ileus.
- To assess complication rates and outcomes associated with RA in MI treatment.
Main Methods:
- Retrospective study of 13 pediatric patients with complicated meconium ileus treated with RA between 1996-2005.
- Data collected included gestational age, surgical details, bowel resection length, and complications.
Main Results:
- The study included 13 patients (3 males, 10 females) with MI, including dilated bowels, perforation, and volvulus.
- Mean bowel resection length was 33.8 cm. Overall survival was 85%.
- Complications occurred in 54% of patients, with 31% experiencing surgical complications such as anastomotic strictures and intestinal obstruction.
Conclusions:
- Resection and primary anastomosis is a safe and effective surgical approach for complicated meconium ileus.
- RA offers benefits including reduced hospital stay and avoidance of stoma-related re-operations.
Abstract:
Various options are available for the surgical treatment of meconium ileus (MI). This paper examines the use of resection and primary anastomosis as the favoured option for the treatment of complicated meconium ileus. This was a retrospective study. All patients (13 children) with MI treated with primary resection and anastomosis (RA) in the 10-year period (1996-2005) at St Mary's Hospital in Manchester were identified. The case notes were retrieved. The gestational age, type of surgery, length of bowel resection and complications were recorded. Out of 13 (3 males, 10 females), 7 had severely dilated bowels, 5 had perforation and 1 had volvulus. Mean length of bowel resection was 33.8 cm (range 20-50 cm). Overall survival in this group was 85%. Seven patients (54%) developed complications. Four (31%) had surgical complications: two anastomotic strictures with adhesions, one adhesive intestinal obstruction and one intra-abdominal drain retraction. Primary resection and anastomosis is a safe option in the treatment of complicated meconium ileus. It has the advantage of less hospital stay and avoids a secondary laparotomy for closure of the stoma.
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