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Updated: Jul 11, 2026

Generation of Subcutaneous and Intrahepatic Human Hepatocellular Carcinoma Xenografts in Immunodeficient Mice
Published on: September 25, 2013
[Subcutaneous seeding of hepatocellular carcinoma after fine-needle percutaneous biopsy]
D Martínez Ramos1, C Villegas Cánovas, V Senent Vizcaíno
1Servicio de Cirugía y del Aparato Digestivo, Hospital General de Castellón. davidmartinez@comcas.es
Abstract:
Subcutaneous tumor seeding after fine-needle percutaneous biopsy for hepatocellular carcinoma is a rarely seen complication. The authors describe a case of subcutaneous neoplastic seeding in a 70-year-old woman with chronic hepatitis C virus complicated by hepatocellular carcinoma. Ultrasonically guided fine-needle aspiration biopsy was performed in segment II of the liver. The neoplastic seeding developed along the needle track used to carry out the fine-needle biopsy. The subcutaneous tumor was excised, and histological examination revealed a well-differentiated hepatocellular carcinoma.

