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Related Experiment Video

Updated: Jul 11, 2026

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability
11:30

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

Published on: July 25, 2025

Lumbar intervertebral instability: a review.

Antonio Leone1, Giuseppe Guglielmi, Victor N Cassar-Pullicino

  • 1Department of Radiology, Catholic University, School of Medicine, Largo A. Gemelli 8, 00168 Rome, and Department of Radiology, Scientific Institute Hospital Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy. a.leonemd@tiscali.it

Radiology
|September 22, 2007
PubMed
Summary

Lumbar intervertebral instability is a debated cause of low back pain. Functional radiography is a common diagnostic tool, but its effectiveness in diagnosing this condition remains unclear.

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Area of Science:

  • Orthopedics and Spine Surgery
  • Radiology and Medical Imaging
  • Biomechanics

Background:

  • Lumbar intervertebral instability is implicated in low back pain and sciatica, influencing surgical decisions for spinal fusion.
  • The condition is poorly understood, with ongoing debate regarding its definition, diagnosis, and treatment.
  • Clinical symptoms are nonspecific, and the link between radiographic findings and patient symptoms is controversial.

Purpose of the Study:

  • To provide an overview of current concepts regarding vertebral instability, particularly degenerative lumbar intervertebral instability.
  • To review imaging modalities used in diagnosing vertebral instability.

Main Methods:

  • Review of current literature on lumbar intervertebral instability.
  • Focus on functional flexion-extension radiography as a widely used diagnostic method.

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Last Updated: Jul 11, 2026

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability
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Published on: July 25, 2025

A Mouse Model of Lumbar Spine Instability
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  • Discussion of various imaging modalities indicated for diagnosing vertebral instability.
  • Main Results:

    • Functional flexion-extension radiography is the most studied and utilized imaging method due to its accessibility and low cost.
    • Despite its use, controversy persists regarding the diagnostic accuracy and clinical correlation of radiographic findings.

    Conclusions:

    • Degenerative lumbar intervertebral instability remains a complex and controversial topic in spinal diagnostics.
    • Further research is needed to clarify diagnostic criteria and the role of imaging in managing low back pain and sciatica.