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Vomiting is a complex physiological response to expel harmful or irritating substances from the body. It's a defensive mechanism triggered by stimuli like poisons, microbial toxins, cytotoxic drugs, and mechanical abdominal distension. The process is centrally coordinated by the vomiting (or emetic) center located in the medulla of the brainstem. This area, rich in muscarinic M1, histamine H1, neurokinin 1 (NK1), and serotonin 5-HT3 receptors, coordinates the act of vomiting through interaction...
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Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
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Functional nausea and vomiting.

Nicholas J Talley1

  • 1Mayo Clinic, Rochester, United States. talley.nicholas@mayo.edu

Australian Family Physician
|September 22, 2007
PubMed
Summary
This summary is machine-generated.

Chronic nausea and vomiting in adults can be categorized into three distinct syndromes: cyclic vomiting syndrome, functional vomiting, and chronic idiopathic nausea. Recognizing these conditions is key for effective diagnosis and treatment.

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Area of Science:

  • Gastroenterology
  • Functional Gastrointestinal Disorders

Background:

  • Many patients experience unexplained chronic nausea and vomiting.
  • Previously misdiagnosed as psychogenic vomiting, evidence suggests these are functional gastrointestinal disorders.

Purpose of the Study:

  • To describe three key syndromes in adults: cyclic vomiting syndrome, functional vomiting, and chronic idiopathic nausea.
  • To aid clinicians in recognizing and differentiating these conditions.

Main Methods:

  • Clinical description and differentiation of syndromes based on symptom presentation and patient history.
  • Review of potential treatments including antimigraine therapy, antidepressants, and distinguishing from rumination.

Main Results:

  • Cyclic vomiting syndrome involves severe, stereotypical episodes with well intervals; cannabis use can mimic this.
  • Functional vomiting is less common, characterized by frequent episodes, and distinguished from rumination.
  • Chronic idiopathic nausea involves frequent nausea without significant vomiting.

Conclusions:

  • Cyclic vomiting syndrome and functional vomiting may respond to antimigraine or tricyclic antidepressant therapies.
  • Distinguishing functional vomiting from rumination requires careful history.
  • Chronic idiopathic nausea treatment is less defined, but antidepressants may offer anecdotal benefit.