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Inhibition of Aspergillus flavus Growth and Aflatoxin Production in Transgenic Maize Expressing the α-amylase Inhibitor from Lablab purpureus L.
Published on: February 15, 2019
An aspergilloma caused by Aspergillus flavus
1School of Medicine, The University of Manchester and Wythenshawe Hospital, The Regional Mycology Laboratory, Manchester, UK. acpasqualotto@hotmail.com
Medical Mycology
|September 22, 2007
Summary
This study reports a rare case of aspergilloma caused by Aspergillus flavus, not the usual Aspergillus fumigatus. The patient also had detectable antibodies, highlighting a unique presentation of fungal lung disease.
Area of Science:
- Mycology
- Pulmonology
- Immunology
Background:
- Chronic pulmonary aspergillosis is a spectrum of fungal lung diseases.
- It typically affects individuals with underlying lung conditions and immune deficiencies.
- Aspergillus fumigatus is the most common causative agent.
Observation:
- This report details a patient diagnosed with an aspergilloma.
- The fungal isolate from the surgical specimen was identified as Aspergillus flavus.
- Serum analysis revealed the presence of precipitating antibodies.
Findings:
- The causative agent was Aspergillus flavus, an uncommon cause of aspergilloma.
- The patient demonstrated a serological response, indicated by detectable precipitating antibodies.
Implications:
- This case expands the known spectrum of fungal pathogens causing aspergilloma.
- It underscores the importance of considering less common Aspergillus species in diagnosing pulmonary fungal infections.
- Further research may elucidate the specific immune responses to Aspergillus flavus in pulmonary infections.
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