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Calf hypertrophy in spinal muscular atrophy
P Ratnagopal1, K Puvandendran, Y S Lee
1Department of Medicine I, Singapore General Hospital.
Singapore Medical Journal
|December 1, 1991
Summary
This study details two rare spinal muscular atrophy variants presenting with calf hypertrophy and slow progression. Findings suggest a chronic denervation issue, possibly central, despite normal nerve conduction tests.
Area of Science:
- Neurology
- Genetics
- Muscle Disorders
Background:
- Spinal muscular atrophy (SMA) encompasses several variants.
- Uncommon SMA variants with specific phenotypes are infrequently reported.
- Gross calf hypertrophy is an unusual presentation in SMA.