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Validation of the erection hardness score.
John P Mulhall1, Irwin Goldstein, Andrew G Bushmakin
1Weill Medical College of Cornell University and Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA. jpm2005@med.cornell.edu
The Erection Hardness Score (EHS) is a reliable and valid tool for assessing erection hardness in clinical trials. This patient-reported outcome effectively measures treatment responsiveness in erectile dysfunction research.
Area of Science:
- Urology
- Clinical Research
- Psychometrics
Background:
- Erection hardness is crucial for erectile function and easily monitored.
- The Erection Hardness Score (EHS) is a single-item patient-reported outcome (PRO) for assessing erection hardness.
Purpose of the Study:
- To psychometrically validate the Erection Hardness Score (EHS).
Main Methods:
- A multinational sildenafil trial dataset (N=307) was analyzed.
- Evaluated test-retest reliability, response distribution, known-groups validity (vs. IIEF), convergent validity (vs. IIEF and QEQ), and treatment responsiveness.
Main Results:
- EHS showed good test-retest reliability and acceptable response quality.
- Demonstrated known-groups validity differentiating ED severity and moderate-to-strong convergent validity.
- EHS exhibited high treatment responsiveness.
Conclusions:
- The EHS possesses desirable measurement properties and is highly responsive to treatment.
- This one-item PRO is robust, easy to use, and validated for assessing erection hardness in clinical trials.
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