[The principles of and some experience with component therapy in acute radiation sickness]

The previous experience gained with the treatment of acute radiation sickness supported during the treatment of the victims to the disaster at the Chernobyl NPP has shown the multimodality treatment to be indispensable for the bone marrow syndrome, particularly in terms of correcting postradiation thrombocytopenia and counteracting bleeding sickness. The use of the whole blood was found to be inadvisable because of the low efficacy, with the risk of transfusion complications being fairly high. Adequate replacement therapy with donor's platelets is capable of a complete modifying of the hemorrhagic syndrome.