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Giant tumefactive perivascular spaces.

Tausha Stephens¹, Hemant Parmar, Wayne Cornblath

¹Department of Radiology, University of Michigan Health System, Ann Arbor, Michigan 48109-0302, USA.

Journal of the Neurological Sciences

|September 25, 2007

Summary

This summary is machine-generated.

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Giant tumefactive perivascular spaces can mimic brain tumors on imaging. Recognizing their characteristic appearance can prevent unnecessary biopsies and guide appropriate patient management.

Area of Science:

Neurology
Radiology
Neuroimaging

Background:

Perivascular spaces (PVS) are normal structures surrounding blood vessels in the brain.
Giant tumefactive perivascular spaces (T-PVS) are an uncommon variant, often presenting as large, cystic lesions.
Distinguishing T-PVS from neoplastic or other pathological processes is crucial for accurate diagnosis.

Observation:

A case study of a 37-year-old male with a history of probable low-grade neoplasm at age 20.
Longitudinal magnetic resonance imaging (MRI) over 17 years revealed stable, multiple cystic masses in the right frontal lobe.
The lesions exhibited signal intensity identical to cerebrospinal fluid (CSF) across all MRI sequences.

Findings:

The observed imaging characteristics were consistent with giant tumefactive perivascular spaces.

Related Experiment Videos

These lesions, despite their size and appearance, demonstrated stability over a long follow-up period.

The key imaging feature is isointensity to CSF on all MRI sequences.

Implications:

Highlights the importance of considering T-PVS in the differential diagnosis of intracranial cystic lesions.
Emphasizes that large, ominous-appearing lesions can be benign and require no intervention.
Suggests that characteristic MRI findings can obviate the need for invasive procedures like biopsy.