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Updated: Jul 11, 2026
A Unified Methodological Framework for Vestibular Schwannoma Research
Published on: June 20, 2017
Immunoreactivity of bovine schwannomas
A B Nielsen1, E C L Jansen1, P S Leifsson1
1Department of Veterinary Pathobiology, Section of Pathology, Faculty of Life Sciences, University of Copenhagen, Ridebanevej 3, DK-1870 Frederiksberg C, Denmark.
Abstract:
Thirty schwannomas from 22 cows were examined immunohistochemically. All were positive for vimentin and Ki-67 but negative for pancytokeratin, neurofilament, and desmin. S-100 immunolabelling varied between and within lesions. The numbers of tumours giving positive results for S-100, neuron-specific enolase (NSE) and glial fibrillary acidic protein (GFAP) were 16, 30 and 25, respectively. It was concluded that vimentin-positive tumours suspected to be schwannomas should also be immunolabelled for NSE and GFAP to confirm the diagnosis.
