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The Ross operation in children: effects of aortic annuloplasty
Robert D Stewart1, Carl L Backer, Neal D Hillman
1Division of Cardiovascular and Thoracic Surgery, Children's Memorial Hospital, Chicago, Illinois 60614, USA.
Insights
Routine aortic annuloplasty did not prevent neoaortic regurgitation after the Ross procedure in children. This surgical modification did not reduce autograft failure requiring reoperation in young patients.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Thoracic Surgery
Background:
- The Ross procedure is a valve replacement technique using a patient's own pulmonary valve (autograft).
- Autograft dilatation and neoaortic regurgitation are known complications after the Ross procedure.
- Routine aortic annuloplasty was implemented to address these complications.
Purpose of the Study:
- To evaluate the effectiveness of routine aortic annuloplasty in preventing autograft failure.
- To assess the impact of aortic annuloplasty on neoaortic valve function and reintervention rates.
Main Methods:
- A retrospective review of 46 children and young adults undergoing the Ross procedure between 1994 and 2005.
- Comparison of neoaortic valve function and reintervention rates between patients with and without aortic annuloplasty.
- Analysis included patients with and without prior aortic valve surgery.
Main Results:
- No early or late deaths occurred during a mean follow-up of 65 months.
- The incidence of autograft repair or replacement for neoaortic regurgitation was similar between groups (13% overall).
- Aortic annuloplasty did not significantly reduce neoaortic regurgitation or neo-sinus of Valsalva dilatation.
Conclusions:
- The Ross procedure is a viable option for pediatric valve replacement with low mortality.
- Routine aortic annuloplasty in this series did not prevent neoaortic regurgitation requiring reoperation.
- Further investigation may be needed to optimize outcomes for the Ross procedure in pediatric patients.
Background:
Autograft dilatation and progressive neoaortic regurgitation after the Ross procedure prompted us to perform routine aortic annuloplasty. The purpose of this review is to evaluate the success of this technical modification in preventing autograft failure requiring reoperation.
Methods:
From 1994 to 2005, 46 children and young adults with a mean age of 12.9 +/- 4.9 years (range, 14 months to 21 years) underwent a Ross procedure; 19 of 46 patients had prior aortic valve surgery. Neoaortic valve function and need for reintervention were compared between patients who had a Ross procedure without annuloplasty (n = 20) and those who had an annular reduction prior to the autograft anastomosis (n = 26).
Results:
There were no early or late deaths during a mean follow-up of 65 +/- 36 months. Mean hospital stay was 6.6 +/- 2.9 days. Two patients required early intervention (eight days) for significant neoaortic regurgitation; one patient required repair of a left ventricular outflow tract pseudoaneurysm a month after emergent Ross procedure for endocarditis, and one patient required replacement of a stenotic homograft at five years. Five patients (13%) required autograft repair (n = 3) or replacement (n = 2) for progressive neoaortic regurgitation, two of the 26 patients had reduction annuloplasty (8%), and three of the 20 patients did not (15%) (p = 0.6). There was a similar incidence of neo-sinus of Valsalva dilatation 37 mm or greater in patients with (53%) and without (36%) annuloplasty (p = 0.5).
Conclusions:
The Ross procedure remains an excellent option for valve replacement in children and young adults given the alternatives and can be performed with very low mortality. However, in this series of Ross operations in children, routine use of aortic annuloplasty failed to prevent neoaortic regurgitation requiring reoperation.
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