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Updated: Jul 11, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Left atrial papillary fibroelastoma: a rare cause of multiple cerebral emboli
Siamak Mohammadi1, Andre Martineau, Pierre Voisine
1Department of Cardiac Surgery, Laval Hospital, Québec City, Québec, Canada.
Insights
Papillary fibroelastomas, often found incidentally via echocardiography, can cause cerebral ischemic attacks. This case highlights an unusual left atrial appendage location requiring surgical excision during bypass surgery.
Area of Science:
- Cardiology
- Neurology
- Pathology
Background:
- Papillary fibroelastomas (PFEs) are increasingly diagnosed due to advances in cardiac imaging, particularly echocardiography.
- These benign cardiac tumors commonly affect the aortic valve but can embolize, leading to neurological events like ischemic attacks.
- The left ventricle is the most frequent nonvalvular site for PFEs.
Observation:
- A 59-year-old male presented with recurrent cerebral ischemic attacks, necessitating coronary artery bypass surgery.
- Initial neurological workup and transthoracic echocardiography were unremarkable.
- Intraoperative transesophageal echocardiography revealed a 5x5 mm pedunculated, mobile mass in the left atrial appendage.
Findings:
- The mass was surgically excised via the left atrial appendage during the coronary artery bypass grafting procedure.
- Microscopic examination confirmed the diagnosis of papillary fibroelastoma.
- This case represents an unusual localization of a PFE.
Implications:
- The findings underscore the importance of considering PFEs in patients with unexplained embolic events, even with initially normal cardiac imaging.
- Surgical management, including excision during other cardiac procedures like bypass surgery, can be effective for PFEs in atypical locations.
- Further research into the optimal diagnostic and management strategies for PFEs in non-traditional sites is warranted.
Abstract:
Papillary fibroelastomas have been increasingly described since the widespread use of cardiac echocardiography. Most often diagnosed incidentally, papillary fibroelastomas may embolize, mainly to the cerebral circulation. The aortic valve is predominantly affected. The left ventricle is the most frequent nonvalvular location. We present a case of a 59-year-old man who had recurrent episodes of cerebral ischemic attacks and required coronary artery bypass surgery. The overall neurologic investigation was normal, including a transthoracic echocardiography. A 5 x 5 mm pedunculated, mobile mass was described on the intraoperative transesophageal echocardiography. The excision was performed through the left atrial appendage during the coronary artery bypass surgery. The microscopic examination demonstrated a papillary fibroelastoma. The unusual localization and management of papillary fibroelastomas are discussed.
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