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Continuous glucose monitoring in children with type 1 diabetes

, Bruce Buckingham, Roy W Beck

    The Journal of Pediatrics
    |September 25, 2007
    PubMed

    Insights

    Daily use of the FreeStyle Navigator continuous glucose monitor is feasible for children with type 1 diabetes (T1D). This technology improved glycemic control and satisfaction, supporting further trials.

    Area of Science:

    • Pediatric Endocrinology
    • Diabetes Technology

    Background:

    • Type 1 diabetes (T1D) management in children requires effective glucose monitoring.
    • Continuous glucose monitoring (CGM) systems offer real-time data for improved glycemic control.

    Purpose of the Study:

    • To assess the feasibility and impact of daily FreeStyle Navigator CGM use in children with T1D.
    • To evaluate user satisfaction and glycemic outcomes associated with the device.

    Main Methods:

    • A 13-week daily use study of the FreeStyle Navigator system involving 30 children with T1D on insulin pumps.
    • Baseline glycemic control was established using a masked CGM before daily use commenced.

    Main Results:

    • Children achieved high daily usage of the CGM, averaging 134-149 hours per week.
    • Mean hemoglobin A1c improved from 7.1% to 6.8% (P = .02), with a significant increase in time within the target glucose range (52% to 60%, P = .01).
    • High user and parent satisfaction was reported, though two subjects experienced skin reactions.

    Conclusions:

    • Daily use of real-time CGM is feasible for children with T1D.
    • The study provides strong support for a randomized controlled trial investigating the benefits of daily CGM in pediatric T1D management.
    Abstract

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