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Related Experiment Video

Updated: Jul 11, 2026

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4

Published on: August 21, 2017

Devic's neuromyelitis optica in an infant case.

Deniz Yuksel¹, Nesrin Senbil, Deniz Yilmaz

¹Department of Pediatric Neurology, Dr Sami Ulus Children's Health and Diseases Training and Research Hospital, Ankara, Turkey. drdeniz_yuksel@yahoo.com.tr

Journal of Child Neurology

|September 25, 2007

Summary

Devic's neuromyelitis optica, a severe neurological syndrome, can affect children. This case report details a 23-month-old boy with Devic's neuromyelitis optica who experienced a poor treatment response and significant long-term effects.

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Published on: April 14, 2014

Area of Science:

Neurology
Pediatric Neurology
Neuroimmunology

Background:

Devic's neuromyelitis optica (NMO) was historically defined as an acute, severe, monophasic syndrome involving myelitis and optic neuritis.
While typically presenting in adults around age 40, NMO has been observed in pediatric populations.
The prognosis for NMO was historically poor with limited treatment options.

Observation:

This report details a case of Devic's neuromyelitis optica in a 23-month-old boy.
The child presented with acute myelitis and optic neuritis, consistent with NMO diagnosis.
The pediatric patient exhibited a poor response to therapeutic interventions.

Findings:

The pediatric patient diagnosed with Devic's neuromyelitis optica developed severe sequelae.
This case highlights the potential for severe outcomes in young children with NMO.
The findings underscore the challenges in managing NMO in the pediatric population.

Implications:

This case emphasizes the need for early recognition and aggressive management of Devic's neuromyelitis optica in children.
Further research is warranted to explore effective therapeutic strategies for pediatric NMO.
Understanding NMO in children is crucial for improving long-term prognoses and reducing disability.