Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pigmented squamous cell carcinoma.

Elizabeth K Satter1

  • 1Department of Dermatology and Dermatopathology, Naval Medical Center, San Diego, CA 92134-2300, USA. elizabeth.satter@med.navy.mil

The American Journal of Dermatopathology
|September 25, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Amelanotic melanoma mimicking an atypical fibrohistiocytic lesion.

The American Journal of dermatopathology·2015
Same author

JAAD Grand Rounds. A 53-year-old woman with multifocal subcutaneous nodules.

Journal of the American Academy of Dermatology·2015
Same author

What is your diagnosis? Secondary syphilis.

Cutis·2014
Same author

Multiple clustered and focally atrophic dermatofibromas (DF).

Dermatology online journal·2014
Same author

What is your diagnosis? Recurrent lobular capillary hemangioma with satellitosis (Warner and Wilson-Jones syndrome).

Cutis·2014
Same author

Cutaneous metastasis of a transitional cell carcinoma.

Dermatology online journal·2014
Same journal

Herpetic Whitlow in Association With a Cutaneous Infiltrate of Chronic Lymphocytic Leukemia.

The American Journal of dermatopathology·2026
Same journal

Basal Cell Carcinosarcoma with an Osteosarcomatous Component: A Case Report Supporting the Diagnostic Utility of SATB2 and TRAP Immunostaining with a Literature Review of 22 Cases.

The American Journal of dermatopathology·2026
Same journal

Demonstration of 23-Gene Expression Profile Test Utility Within PRAME Immunohistochemistry Results: A Case Series.

The American Journal of dermatopathology·2026
Same journal

On the Progression From Early-to Late-Stage Melanoma: A Potential Sequence of Molecular Events Using Data From Droplet Digital PCR and Array Comparative Genomic Hybridization, A Pilot Study.

The American Journal of dermatopathology·2026
Same journal

Montgomery Tubercles in the Male Areola: Histological Observations and a Brief About Past Investigators.

The American Journal of dermatopathology·2026
Same journal

Metastatic Syringocystadenocarcinoma Papilliferum Mimicking Cutaneous Squamous Cell Carcinoma of Unknown Primary in a Young Patient.

The American Journal of dermatopathology·2026
See all related articles

Pigmented squamous cell carcinoma (SCC) is rare, especially on the skin. This case highlights an acantholytic pigmented SCC on the cheek, emphasizing the need for careful diagnosis.

Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Melanin-containing melanocytes are occasionally found in epithelial neoplasms.
  • Pigmented squamous cell carcinoma (SCC) is a rare entity, accounting for only 0.01% to 7% of all SCCs.
  • Most reported cases of pigmented SCC originate in the oral and ocular mucosa.

Observation:

  • A 61-year-old Caucasian male presented with a large, blue-black nodule on his left cheek.
  • The clinical presentation was suspicious for melanoma.
  • Histological evaluation revealed an acantholytic pigmented squamous cell carcinoma.

Findings:

  • The case represents a rare instance of skin-originating pigmented SCC.
  • Acantholytic features were noted in the pigmented SCC.

Related Experiment Videos

  • The differential diagnosis between melanoma and pigmented SCC is crucial.

    • Implications:

    • This case underscores the importance of considering pigmented SCC in the differential diagnosis of pigmented skin lesions.
    • Further review of previous cases and diagnostic criteria is warranted.
    • Accurate histological evaluation is essential for correct diagnosis and patient management.