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Updated: Jul 11, 2026

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction
Published on: August 17, 2022
Non-invasive evaluation of coronary vasospasm using a combined hyperventilation and cold-pressure-test perfusion CMR
Ali Yilmaz1, Heiko Mahrholdt, Anastasios Athanasiadis
1Division of Cardiology, Robert-Bosch-Krankenhaus, Stuttgart, Germany.
Abstract:
Coronary vasospasm is a severe vasoconstriction of an epicardial coronary artery, which may lead to myocardial ischemia and cause symptoms of angina. The gold-standard for diagnosing coronary vasospasm is to perform an intracoronary provocation test and to demonstrate the epicardial vasoconstriction by coronary angiography. We report the case of a patient with coronary vasospasm in whom we succeeded to non-invasively provoke and subsequently non-invasively demonstrate myocardial ischemia by perfusion cardiovascular magnetic resonance (CMR).
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