Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Heart Failure IV: Classification and Diagnostic Evaluation

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...

Exercise and Cardiovascular Response

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...

Heart Failure VII: Nursing Interventions

Heart Failure VII: Nursing Interventions

The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...

Heart Failure I: Introduction

Heart Failure I: Introduction

Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...

Pathophysiology of Heart Failure

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...

Imbalances in Cardiac Output

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Circadian rhythms of core and skin temperature in heart failure.

European journal of heart failure·2026

Same author

Enhanced cardiac sympathetic innervation predicts systolic function improvement and outcome in dilated cardiomyopathy.

Cardiology journal·2026

Same author

Gated single photon emission computed tomography imaging of left ventricular mechanical dyssynchrony: Predictive value in cardiac resynchronization therapy candidates.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology·2026

Same author

Effects of sodium-glucose cotransporter 2 inhibitors on cardiac metabolism, assessed by phosphorus magnetic resonance spectroscopy, in patients with heart failure.

European journal of heart failure·2026

Same author

Update on the epidemiology, healthcare utilization, and economic burden of heart failure in Poland (2015-2025).

Kardiologia polska·2026

Same author

Inflammasomes as Potential Therapeutic Targets to Prevent Chronic Active Viral Myocarditis-Translating Basic Science into Clinical Practice.

International journal of molecular sciences·2025

Search research articles

Related Experiment Video

Updated: Jul 11, 2026

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models

Published on: July 21, 2023

[Heart failure and physical activity].

Piotr Podolec¹, Paweł Rubiś

¹Klinika Chorób Serca i Naczyń, Instytutu Kardiologii Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowskim Szpitalu Specjalistycznym im. Jana Pawła II. ppodolec@interia.pl

Przeglad Lekarski

|September 26, 2007

Summary

Heart failure (HF) impairs exercise capacity due to complex pathophysiology. Exercise testing, including cardiopulmonary exercise tests (CPX), objectively evaluates functional activity and guides cardiac rehabilitation for improved outcomes.

More Related Videos

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program

Published on: April 19, 2019

Related Experiment Videos

Last Updated: Jul 11, 2026

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models

Published on: July 21, 2023

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program

Published on: April 19, 2019

Area of Science:

Cardiology
Exercise Physiology

Context:

Heart failure (HF) presents a growing global health challenge with significant morbidity.
Reduced exercise capacity is a primary limitation for patients with HF, impacting daily life and prognosis.

Purpose:

To review the pathophysiology of impaired exercise capacity in HF.
To discuss methods for assessing exercise tolerance in HF patients.
To highlight the role and benefits of exercise training and cardiac rehabilitation in HF management.

Summary:

Impaired exercise capacity in HF stems from central pump dysfunction and peripheral alterations.
Objective assessments like cardiopulmonary exercise testing (CPX) and maximal oxygen uptake (VO2max) are crucial for evaluating functional status.
Stress echocardiography can assess cardiac function under load, correlating with exercise duration.

Impact:

Exercise training and cardiac rehabilitation are beneficial for HF patients, improving exercise duration, quality of life, and reducing mortality.
Careful patient selection, supervision, and follow-up are essential for safe and effective exercise interventions in HF.