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Meperidine prolongs lidocaine caudal epidural anaesthesia in the horse

Rafael Derossi1, Ulisses Medeiros, Ricardo G de Almeida

  • 1Department of Veterinary Medicine, Surgery and Anaesthesiology, Faculty of Veterinary Medicine, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil. derossi@nin.ufms.br

Veterinary Journal (London, England : 1997)
|September 26, 2007
PubMed

Insights

Combining meperidine (MP) and lidocaine (LD) for epidural anesthesia in horses provided longer-lasting analgesia in the tail, perineum, and hind limbs compared to using either drug alone.

Area of Science:

  • Veterinary Anesthesiology
  • Equine Pharmacology

Background:

  • Epidural anesthesia is utilized in equine practice.
  • Meperidine (MP) and lidocaine (LD) are commonly used analgesics.

Purpose of the Study:

  • To compare the efficacy of caudal epidural meperidine (MP), lidocaine (LD), and a combination (MPLD) in horses.
  • To evaluate the duration of analgesia and potential side effects.

Main Methods:

  • Six mature horses received MP (0.3 mg/kg), LD (0.2 mg/kg), or MPLD (MP 0.3 mg/kg + LD 0.2 mg/kg) epidurally.
  • Treatments were administered with at least a 1-week interval.
  • Analgesia, ataxia, sedation, cardiovascular, respiratory, and temperature effects were monitored.

Main Results:

  • Epidural MPLD produced a significantly longer duration of analgesia in the tail, perineum, and upper hind limbs.
  • Individual MP and LD provided shorter durations of analgesia.

Conclusions:

  • The combination of meperidine and lidocaine via epidural administration offers prolonged analgesia in horses.
  • MPLD is a potentially effective option for procedures requiring extended analgesia in the specified regions.

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