Related Experiment Video
Updated: Aug 19, 2026

In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears
Published on: February 21, 2018
Bilateral Menière's disease in surgical versus nonsurgical patients
S Rosenberg1, H Silverstein, J Flanzer
1Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia.
Abstract:
In patients with Menière's disease, the possibility of developing Menière's disease in the uninvolved ear is of great concern. In this study, the incidence of bilateral Menière's disease (BMD) in medically treated patients was found to be 17 percent, while in surgically treated patients it was significantly lower, 5.9 percent (p less than 0.01). The incidence of BMD for each surgical procedure was as follows: 9 percent after endolymphatic subarachnoid shunt (n = 101), 7 percent after cochleovestibular neurectomy (n = 100), 6 percent after cochleosacculotomy (n = 18), and 0 percent after vestibular nerve section (n = 73). The average duration of disease prior to surgery was 6.3 years. Seventy-two percent of the patients who developed BMD did so within 5 years of the onset of their symptoms. Proper patient selection is the most likely explanation for the low incidence of BMD among surgically treated patients.

