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[Multiple paragangliomas: about two cases].

M Alaoui1, A Bouzarwata, R El Idrissi

  • 1Service de chirurgie vasculaire, CHU hôpital Ibn Sina, Rabat, Morocco. alamus@caramail.com

Archives Des Maladies Du Coeur Et Des Vaisseaux
|September 26, 2007
PubMed
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Multiple paragangliomas are rare tumors. This study reports two complex cases, highlighting surgical and embolization strategies for carotid, aortic, and jugulo-tympanic localizations.

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Neurosurgery

Background:

  • Paragangliomas are rare, slow-growing tumors with diagnostic and therapeutic challenges.
  • Carotid and jugulo-tympanic sites are most frequent; aortic localization is infrequent.
  • Multiple paragangliomas, especially familial forms, can present with diverse localizations.

Observation:

  • Two cases of chemodectoma (paraganglioma) with multiple, complex localizations are presented.
  • Case 1: 44-year-old female with bilateral carotid and aortic arch paragangliomas.
  • Case 2: Patient with double aortic, carotid, and tympano-jugular paragangliomas.

Findings:

  • Surgical removal is the primary treatment for most paraganglioma localizations.
  • Therapeutic strategies were tailored: carotid and aortic sites surgically treated; tympano-jugular site treated with embolization.

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  • Both patients experienced uneventful postoperative periods; one case received adjunctive radiotherapy.

    • Implications:

    • Management of multiple paragangliomas requires individualized therapeutic strategies.
    • Surgical intervention, often starting with carotid localization, is key.
    • Embolization offers an alternative for specific sites like tympano-jugular paragangliomas.